27.7.2023

Faster analysis of human proteomes enabled by narrow-window data-independent acquisition

Date: 27. 7. 2023
Time: 8:00 PDT | 11:00 EDT | 16:00 BST | 17:00 CEST
Registration: here

Scaling proteomics with the Thermo Scientific Orbitrap Astral mass spectrometer.

This webcast will introduce the new ultra-fast scanning Orbitrap Astral mass spectrometer for comprehensive and high-throughput quantitative proteomics.

The performance of the new instrument is evaluated using narrow-window data-independent acquisition (DIA) in combination with short LC gradients. The narrow-window DIA allows acquisition of comprehensive human proteomes in a few hours, with comparable depth to next-generation RNA sequencing and with 10x higher throughput compared to the current state-of-the-art.

Optimization of instrument acquisition parameters for comprehensive proteome coverage with high quantitative precision and accuracy, as well as high-throughput biomedical applications, will be demonstrated.

Learn:

Quantitative performance of the Orbitrap Astral mass spectrometer for data-independent acquisition
Benefits of narrow-window data-independent acquisition (DIA)
How to acquire comprehensive human proteomes within hours

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This webcast has been produced by Thermo Fisher Scientific, who retails sole responsibility for content. About this content.

Speaker:

Jesper Olsen, Professor, University of Copenhagen

Prof. Jesper Olsen studied analytical chemistry and obtained his Ph.D. in biochemistry and molecular biology in the laboratory of Matthias Mann where he was involved in developing high-resolution MS-based proteomics and phosphoproteomics workflows. He then moved to Copenhagen and, in 2012, was promoted to vice director of Novo Nordisk Foundation for Protein Research at University of Copenhagen, and in 2014 full professor.