27.9.2022
Live webinar: New developments in mass spectrometry-based single-cell proteomics
Time: 8:00 a.m. PT | 11:00 a.m. ET | 16:00 BST | 17:00 CEST
More information: here
The analysis of single-cell proteomes has recently become a viable complement to transcriptomics and genomics studies, as proteins are the main driver of cellular functionality and mRNA levels are often an unreliable proxy of such. Both multiplexed and label-free mass spectrometry-based approaches with single-cell resolution have attributed surprising heterogeneity to cell populations believed to be homogenous. Even though specialized experimental designs and instrumentation have demonstrated remarkable advances, the efficient sample preparation of single cells still lags behind.
In this live webinar, learn how Karl Mechtler has developed an end-to-end workflow to efficiently prepare and analyze samples for single-cell proteomics by mass spectrometry. A cellenONE proteoCHIP sample preparation device, coupled to Thermo Scientific Orbitrap mass spectrometers, comprises a single-cell proteomics workflow solution with surprising sensitivity and throughput.
Attend this webinar to learn how to:
- Identify key challenges and solutions for single-cell proteomics experiments
- Understand an end-to-end workflow for single-cell proteomics sample preparation and analysis
- Learn how mass spectrometry approaches can be applied to single-cell proteomics
Who should attend:
- Proteomics researchers
- Scientists
- Laboratory managers
Speakers:
- Karl Mechtler, Head of Protein Chemistry Facility at IMP, IMBA, GMI, Head of Mass Spectrometry VBCF, Vienna BioCenter
- David Hartlmayr, Proteomics Application Specialist in the Single-Cell Proteomics department at Cellenion, Lyon
- Manuel Matzinger, Postdoctoral scientist and deputy head for method development in the Proteomics Core Facility at the IMP Vienna