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Expert insights for microscopists

Dear Scientist,

In collaboration with renowned scientists from around the world, we have put together a series of exciting webinars featuring a broad range of microscopy techniques. If you missed the live broadcast or would simply like to replay the recordings, click to access these informative talks below.

Watch Prof Dr Eric Reits, as he shares his research into neurodegenerative disorders. Reits’ group are experts on the subject of Huntington’s disease and work towards identifying leads for potential therapies.

Join Prof Dr Peter Horvarth, as he presents his work on single cell-based large-scale microscopy experiments. This novel targeting approach includes the use of machine learning models and ultimately enables successful DNA and RNA sequencing, proteomics, lipidomics and targeted electrophysiology measurement on selected cells.
 

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Visualising protein degradation and aggregation in the living cell

In this webinar you will find out how:

  • Both proteasomes and ubiquitin are reversibly recruited to aggregates and proteasomes are able to degrade these proteins
  • Different microscopy approaches, including live cell imaging and confocal FRAP and FLIM, are used in this valuable research into neurodegenerative disorders
  • The use of different fluorescent labels, activity-based probes and quenched substrates uncovered key information

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Life beyond the pixels: Deep learning methods for single cell analysis

As part of his work on single cell-based large-scale microscopy, involving confocal, light sheet and laser microdissection, Peter talks about:

  • A novel microscopic image correction method designed to eliminate illumination and uneven background effects
  • New single-cell image segmentation methods using differential geometry, energy minimization and deep learning methods
  • The Advanced Cell Classifier (ACC), a machine learning software tool capable of identifying cellular phenotypes based on features extracted from the image

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